Searchable abstracts of presentations at key conferences in endocrinology

ea0020p372 | Diabetes and Cardiovascular | ECE2009

N-acetylcysteine is able to reduce the oxidation status and the endothelial activation after a high-glucose content meal in patients with type 2 diabetes mellitus

Masha Andi , Brocato Loredana , Dinatale Stefano , Mascia Cinzia , Biasi Fiorella , Martina Valentino

Introduction: Post-prandial hyperglycaemia seems to play a pivotal role in the pathogenesis of cardiovascular complications of diabetes mellitus, as it leads to oxidative stress which in turn causes reduced NO bioavailability that produce endothelial activation.Aim: Aim of the study was to assure that the administration of N-acetylcysteine (NAC), thiolic antioxidant, is able to decrease oxidation status and endothelial activation after a high-gluc...